CP (C-Peptide)

C-peptide is a peptide which is made when proinsulin is split into insulin and C-peptide. They split when proinsulin is released from the pancreas into the blood in response to a rise in serum glucose - one C-peptide for each insulin molecule. C-peptide is the abbreviation for "connecting peptide", although its name was probably also inspired by the fact that insulin is also composed of an "A" chain and a "B" chain. C-peptide was discovered in 1967. The first documented use of the C-peptide test was in 1972. It should not to be confused with c-reactive protein or Protein C. C-peptide functions in repair of the muscular layer of the arteries. C-peptide also exerts beneficial therapeutic effects on many complications associated with diabetes mellitus, such as for instance diabetic neuropathy and other diabetes-induced ailments. In the kidneys, C-peptide prevents diabetic nephropathy, and in the heart blood flow is improved in diabetic patients.

Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested.

ELISA: 1:100-1:5000
Western Blot: 1:50-400
Immunohistochemistry (frozen): 1:50-500
Immunohistochemistry (paraffin): 1:10-100
Immunocytochemistry: 1:50-500
Optimal dilutions to be determined by the researcher.

QPLVSSPLRGEAGVLP

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Pab

IgY

rabbit

chicken

~0.5mg/ml

Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.

Purified by immunoaffinity chromatography.

Synthetic peptide corresponding to chicken CP, QPLVSSPLRGEAGVLP, conjugated to KLH.

Recognizes chicken CP.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.