Morus rubra Lectin (MRL) - Pure

Morus rubra lectin (MRL) is isolated from red mulberry was purified to homogeneity from the leaves by a single-step immobilized metal ion affinity chromatography (IMAC) procedure. The molecular weight of MRL is around 52,000 and has a specificity towards galactose, D-galactosamine and N-acetyl-D-galactosamine. MRL also has haemagglutination activity towards different erythrocyte blood groups. MRL has an isoelectric point that ranges between pH 4 and pH 11. Lectin bonding with EDTA did not alter the hemagglutinin activity which demonstrates that metal ions are not required for activity.

Specifications:

Abbreviation: MRL

Material Source: Red Mulberry

Preferred Sugar Specificity: Galactose, N-Acetylgalactosamine

Inhibiting or Eluting Sugar: Galactose

Divalent Ions: None Required

Mitogenic Activity: No

Lyophilized or Liquid: Lyophilized

Storage Temperature: -20°C

Hazardous Shipping: Non-hazardous

Application

Cancer biology

References

Sureshkumar, T., and Priya, S. Purification of a lectin from M. rubra leaves using immobilized metal ion affinity chromatography and its characterization. Appl Biochem Biotechnol. (2012) 168(8):2257-67.