Human Perforin ELISpot Pair, 10 x 96-well
Product Images
Specifications
| Product Data | |
| Format | 10 x 96-well |
| Assay Type | Enzyme-Linked ImmunoSpot (ELISpot) |
| Signal | Colorimetric |
| Specificity | Recognizes natural human Perforin |
| Cross Reactivity | No cross reactivity with other human soluble molecules |
| Components | ELISpot matched antibody pairs are extensively validated and include pre-titrated capture antibody and biotinylated detection antibody. Antibodies are supplied in quantities sufficient for 10 x 96 samples. |
| Background | The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] |
| Gene Symbol | PRF1 |
| Gene ID | 5551 |
Documents
| SDS |