Custom service : TARGATT™ Fast and Site-Specific shRNA Knock-down Mice Service
In vivo shRNA Knock-down Mouse model in as little as 3 months
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Gene knock-out technology using short hairpin RNA (shRNA) to inhibit expression of the corresponding gene has been widely used in gene function studies, drug discovery, and disease research.
Our TARGATT™ technology allows you to generate an in vivo shRNA Knock-down Mouse model in as little as 3 months.
To generate your TARGATT™ shRNA Mouse, you will need a TARGATT™ Kit (AST#) to prepare the DNA and a TARGATT™ mouse colony (AST#) for pronuclear injection. All steps are also available as individual service options.
- shRNA copy number is controlled
- Specific locus insertion guarantees the expression of shRNA
- shRNA expression can be regulated by a tissue-specific promoter
- Founder mice can be generated in as little as 3 months
- Full service including shRNA design, construction, and validation is available