Human IL-5 ELISpot Pair, 10 x 96-well

CAT#: EA101819

Human IL-5 ELISpot Pair, 10 x 96-well


Product Images

Specifications

Product Data
Format 10 x 96-well
Assay Type Enzyme-Linked ImmunoSpot (ELISpot)
Signal Colorimetric
Specificity Recognizes both natural and recombinant human IL-5
Cross Reactivity No cross reactivity with other human cytokines
Components ELISpot matched antibody pairs are extensively validated and include pre-titrated capture antibody and biotinylated detection antibody. Antibodies are supplied in quantities sufficient for 10 x 96 samples.
Background This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]
Gene Symbol IL5
Gene ID 3567

Documents